Endocrine Abstracts

Introduction: Epilepsy and anti-epileptic medications can be associated with various endocrine disorders namely, polycystic ovary syndrome, premature ovarian failure, hypothalamic amenorrhoea, functional hyperprolactinaemia and rarely galactorrhoea. Here, we present a lady who developed intermittent episodes of galactorrhoea suspected to be due to primary generalized seizures.Case report: A 50-year-old lady was referred for investigation of elevated prol...

Introduction: The prevalence of vitamin D deficiency has been increasing worldwide. This can be due to inadequate exposure to sunshine, dietary deficiency, dark skin, covering the whole body due to religious custom. Here, we present an interesting case of a newborn baby with severe hypocalcemia developing seizures and severe cardiac problems secondary to maternal vitamin D deficiency.Case history: A newborn male baby was admitted to cardiac ITU with a hi...

Introduction: Sheehan’s syndrome is hypopituitarism occurring due to pituitary infarction secondary to severe post-partum haemorrhage. Here, we are presenting an interesting case history of Sheehan’s syndrome diagnosed 15–20 years after its onset.Case history: A 47-year-old lady attended emergency room (ER) with recurrent episodes of nausea, vomiting and dizziness on standing. Initial evaluation revealed hypotension and the random...

Hypopituitarism as a consequence of snake bite is rare. However, there are a few case reports from India and adjacent South-East Asian countries. We present a case of hypopituitarism secondary to snake bite where the diagnosis was significantly delayed. A 42-year-old gentleman presented as out-patient with a 10 years history of generalized weakness, lethargy, coarse facial features, reduced libido, reduced socialization and depression. He had an acute illness following a snake...

A 24-year-old women (wt 63 kg, BMI 23) presented with history of secondary amenorrhea. Menarche occurred at age 16 years and was followed by a regular cycle (7/35). She started the combined oral contraceptive pill (OCP) at 18 years of age for menorrhagia and stopped this 16 months before her presentation, before undergoing elective surgery. Four months after discontinuing the OCP she experienced a single episode of PV bleeding, but otherwise remained amenorrhoeic. Past history...

Cushing’s syndrome (CS) is a rare endocrine problem in children. Most of the cases in children are iatrogenic in nature due to extensive usage of topical, inhaled and oral corticosteroids. Endogenous hypercortisolism in children is mainly because of ACTH-dependent pituitary adenomas and constitutes ~70–80% of CS in children. ACTH-independent CS is rare in children above 5 years of age. Here, we are presenting a rare case of ACTH-independent macronodular adrenal hyper...

Vitamin D deficiency with secondary hyperparathyroidism is common in South-east Asia. In contrast, primary hyperparathyroidism is relatively rare. We present a case of severe proximal myopathy with significant diagnostic delay.A 23-year-old lady presented with a 2 years history of lower back pain, radiating to both groins and upper thighs associated with recurrent falls. Her pain and weakness progressed insidiously leading to difficulty standing or walki...

In patients presenting with a diffusely enlarged hard thyroid gland the differential diagnosis lies between thyroid carcinoma, lymphoma, and Riedel’s thyroiditis. We present a case of Riedel’s thyroiditis with multifocal nodular sclerosis, which improved with levothyroxine replacement.A 40-year-old woman presented with a 3 months history of neck swelling, dysphagia and breathlessness on exertion. Examination revealed a hard, fixed, diffuse goit...